I have a system with Summits in the front with 2 Descent i's and 2 Descents behind the listening position. The 4 Descents are near but not in the corners and are "aimed" at the center of the listening room. I also have a Stage center channel and 2 Script i's for surround listening.
Most of my listening is surround for video and two channel for music. Since I put in the two new Descents (which are theoretically better than the older ones altough bass information is pretty nondirectional and often felt rather than heard at the subwoofer level) the system imaging has improved rather markedly. There is a "thereness" that just wasn't there before, suggesting at least subjectively that sharing low bass information among several speakers helps out the higher frequencies as well. The technical papers on multiple subwoofer installations also suggest that this may occur in a 4 subwoofer set up.
Regarding the CLX's and the Summits. I have heard the CLZ (final version) before they were discontinued and AB'd them against the Ascent i's before purchase. My observation was that they had insufficient and unclear bass. The panel size also tended to interfere with optimal imaging which was better on the smaller ESL hybrid speakers. While the CLX's using better panel technology may improve some of the frequency anomalies, they will still require bass reinforcement making them probably more expensive than a straightforward pair of Summits. I am not sure about the imaging but my experience with larger ESLs ( and I have had many including Koss 1As, various Accoustats, etc) is that they are more subject to having the image "stick" on the panels. They also are harder to place in a room. The advantage of a lack of crossover may be mitigated by the need for subwoofer reinforcement.
If and when my dealer gets CLX's I will have an A-B comparison opportunity and will do so with an open mind.