I agree completely. It is particularly true of a lot of engineering minds.....the engineering texts are explicit, so there can be no difference, so they are not going to even listen, even if it costs nothing to do so! That is a closed mind. I like to keep an open mind when I listen.
So Mark, please do me a favour and go to your nearest high end dealer and compare a length of Radio Shack interconnect with a high end interconnect. If you hear no difference I will not respect you any less
But please, no instant switching; I've always wondered what those switch boxes contribute. Take your favourite CD, listen to a few tracks, then switch and listen. And don't listen with your head in a vise, concentrating on every note; relax and enjoy the music. If there is a difference you will hear it, whether you want to or not. I'm assuming, of course, that your hearing is not crap, deafened by those helos.
By the way, much is made of auditory memory being fleeting, but I've sometimes heard a new instrument in a familiar recording, then gone back to the old config and listened again. The instrument was not there, so my auditory memory was fine.