..... I found out the hard way since the center speaker (Cinema i) is quite different than my front left & right speakers (ReQuest). I have Classe' amplifiers for the front 3 channels but the Cinema is out-of-character when trying to match with the ReQuests. The best I can describe it is that it has a boomy (weighty) mid-bass that seems to drag the center channel from keeping up with the faster ReQuest panels. That may be due to the higher crossover point of the Cinema i (300Hz) vs the ReQuest's 200Hz. The higher crossover point on the Cinema causes the (lower) mid-bass to bleed into the woofers and I can definitely hear the discrepancies between the Cinema and the ReQuest. There's also the "tizziness" of the Cinema's tweeter that does not match with the ReQuest panels. In my case, the Cinema is always drawing my attention to itself, especially the flanking 5 1/4" woofers, just due to the fact that it's built differently. I had the same experience when I brought home the Logos and the Theater for auditioning, close but no cigar!
In my opinion, the "ideal" set-up would be to have identical amplifiers AND identical speakers, for example, 3 ReQuests for the front-channels in my system!
Spike